Chemical structure

Chemical Name: 3-Oxoestr-4-en-17beta-yl 3-phenylpropionate;

Alternative: 17beta-Hydroxyestr-4-en-3-one 3- phenylpropionate.

Molecular Formula: C27H34O3

Molecular Weight: 406.6

Group
ATC Classification:
(Anabolic Agents for Systemic Use)
(Anabolic steroids)

Synonyms Nandrolone Hydrocinnamate; Nandrolone Phenpropionate; 19-Norandrostenolone Phenylpropionate; Nortestosterone Phenylpropionate; NSC-23162

CAS number: 62-90-8

Main brand names, main trade names
Activin; Durabolin; Durabolin; Hybolin; Nandrolone Phenpropionate Injection; 23, Nandrolone Phenylpropionate Injection; Stenabolin; Docabolin (multi-ingredient preparation); Docabolina (multi-ingredient preparation)

Main manufacturers, main importers

SUMMARY
Main risks and target organs There is no serious risk from acute poisoning, but chronic use can cause harm. The main risks are those of excessive androgens: menstrual irregularities and virilization in women and impotence, premature cardiovascular disease and prostatic hypertrophy in men. Both men and women can suffer liver damage with oral anabolic steroids containing a substituted 17-alpha-carbon. Psychiatric changes can occur during use or after cessation of these agents.

Summary of clinical effects
Acute overdosage can produce nausea and gastrointestinal upset. Chronic usage is thought to cause an increase in muscle bulk, and can cause an exageration of male characteristics and effects related to male hormones.
Anabolic steroids can influence sexual function. They can also cause cardiovascular and hepatic damage. Acne and male- pattern baldness occur in both sexes; irregular menses, atrophy of the breasts, and clitoromegaly in women; and testicular atrophy and prostatic hypertrophy in men.

Diagnosis
The diagnosis depends on a history of use of oral or injected anabolic steroids, together with signs of increased muscle bulk, commonly seen in "body-builders". Biochemical tests of liver function are often abnormal in patients who take excessive doses of oral anabolic steroids. Laboratory analyses of urinary anabolic steroids and their metabolites can be helpful in detecting covert use of these drugs.

First aid measures and management principles
Supportive care is the only treatment necessary or appropriate for acute intoxication. Chronic (ab)users can be very reluctant to cease abuse, and may require professional help as with other drug misuse.